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Nolvadex or Clomid are common supplements taken to raise testosterone levels following a cycle of anavaric to progesterone, but research in humans has found some adverse effects. In a new study published in The Journal of Clinical Endocrinology or Metabolism, three groups of men who were taking a pill called Proviron® experienced side effects ranging from mild insomnia and tiredness, to severe and irreversible loss of libido, ejaculatory dysfunction, and mood swings. After a 12-week study, two of the three groups (Nolvadex and Clomid) experienced clinically significant negative effects with Clomid at 12 weeks, while neither group experienced a detectable effect with Nolvadex. However, if a placebo was added to the pill, Nolvadex performed as well as Clomid, while in both groups the mood swings of both drugs were diminished by approximately 20 percent, and none of the side effects were clinically significant. "Proviron® was well-tolerated for our participants," study author Dr. John Kvitkot said. "We have no reason to think that such a drug would not also have the effects of propranolol and may be equally effective," he added. Dr. Kvitkot was not involved in the study, but he co-authored the 2012 article "Cognitive Impairment Associated with Proviron® Intrauterine Exposure: Implications for Postmenopausal Women ," which was published in The Journal of the American College of Obstetricians and Gynecologists. The article included a review of eight studies that examined the cognitive effects of exogenous estrogens, and concluded that "the use of high concentration doses of estrogen in young adult women may impair cognitive function in the period, especially among the elderly." Proviron® is a combination of a progestin with an anavaric antiandrogen (in this case, spironolactone). It is also sold by generic drug stores. Proviron® is usually combined with anavaric and spironolactone due to its ability to lower inhibitions in the body. The drug also has a long-term effect in reducing depression and increasing confidence. While these benefits are often overstated, Proviron® seems to be doing more to promote well-being than many other treatments. Kvitkot is currently working with two more studies to look at the potential cardiovascular effects of Proviron®. "The effect of progesterone on cardiovascular events has been extensively studied in humans and is Similar articles:

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Caffeine anabolic steroids and growth hormones, gear use steroids
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